Antimalarial action of hydroxamate-based iron chelators and potentiation of desferrioxamine action by reversed siderophores.

Hydroxamate-based chelators of iron are potent inhibitors of in vitro growth of Plasmodium falciparum. Two types of such chelators, the natural desferrioxamine and the synthetic reversed siderophore RSFileum2, are prototypes of antimalarial agents whose action spectra differ in the speed of action,...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Golenser, J, Tsafack, A, Amichai, Y, Libman, J, Shanzer, A, Cabantchik, Z I
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7695330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.1.61
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