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Reciprocal domain evolution within a transactivator in a restricted sequence space

Although the concept of domain merging and shuffling as a major force in protein evolution is well established, it has been difficult to demonstrate how domains coadapt. Here we show evidence of coevolution of the Sinorhizobium meliloti NifA (SmNifA) domains. We found that, because of the lack of a...

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Hlavní autoři: Juárez, Katy, Flores, Humberto, Dávila, Sonia, Olvera, Leticia, González, Víctor, Morett, Enrique
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC16236/
https://ncbi.nlm.nih.gov/pubmed/10716734
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