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Reciprocal domain evolution within a transactivator in a restricted sequence space

Although the concept of domain merging and shuffling as a major force in protein evolution is well established, it has been difficult to demonstrate how domains coadapt. Here we show evidence of coevolution of the Sinorhizobium meliloti NifA (SmNifA) domains. We found that, because of the lack of a...

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Detalhes bibliográficos
Main Authors: Juárez, Katy, Flores, Humberto, Dávila, Sonia, Olvera, Leticia, González, Víctor, Morett, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16236/
https://ncbi.nlm.nih.gov/pubmed/10716734
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