Yeast Ume6p repressor permits activator binding but restricts TBP binding at the HOP1 promoter

Ume6p plays essential roles in the regulation of early meiotic genes in Saccharomyces cerevisiae. Ume6p exerts repression via recruitment of the Sin3p-Rpd3p histone deacetylase and Isw2p chromatin remodeling complexes. The transcriptional step that is ultimately inhibited by Ume6p is unknown. Here,...

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Hauptverfasser: Shimizu, Mitsuhiro, Takahashi, Keiko, Lamb, Teresa M., Shindo, Heisaburo, Mitchell, Aaron P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2003
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC162329/
https://ncbi.nlm.nih.gov/pubmed/12799429
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