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Abnormal passive chloride absorption in cystic fibrosis jejunum functionally opposes the classic chloride secretory defect

Due to genetic defects in apical membrane chloride channels, the cystic fibrosis (CF) intestine does not secrete chloride normally. Depressed chloride secretion leaves CF intestinal absorptive processes unopposed, which results in net fluid hyperabsorption, dehydration of intestinal contents, and a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Russo, Michael A., Högenauer, Christoph, Coates, Stephen W., Santa Ana, Carol A., Porter, Jack L., Rosenblatt, Randall L., Emmett, Michael, Fordtran, John S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162286/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12840066/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17667
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