Abnormal passive chloride absorption in cystic fibrosis jejunum functionally opposes the classic chloride secretory defect

Due to genetic defects in apical membrane chloride channels, the cystic fibrosis (CF) intestine does not secrete chloride normally. Depressed chloride secretion leaves CF intestinal absorptive processes unopposed, which results in net fluid hyperabsorption, dehydration of intestinal contents, and a...

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Bibliografske podrobnosti

izdano v:	J Clin Invest
Principais autores:	Russo, Michael A., Högenauer, Christoph, Coates, Stephen W., Santa Ana, Carol A., Porter, Jack L., Rosenblatt, Randall L., Emmett, Michael, Fordtran, John S.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 2003
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162286/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12840066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17667
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