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Diacylglycerol kinase δ regulates protein kinase C and epidermal growth factor receptor signaling
Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol (DAG) to terminate its signaling. To study DGKδ, we disrupted its gene in mice and found that DGKδ deficiency reduced EGF receptor (EGFR) protein expression and activity. Similar to EGFR knockout mice, DGKδ-deficient pups were born with open...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1622849/ https://ncbi.nlm.nih.gov/pubmed/17021016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604104103 |
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