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Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice
The homeobox transcription factors Engrailed-1 and Engrailed-2 are required for the survival of mesencephalic dopaminergic neurons in a cell-autonomous and gene-dose-dependent manner. Because of this requirement, the cells die by apoptosis when all four alleles of the Engrailed genes are genetically...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1622807/ https://ncbi.nlm.nih.gov/pubmed/17015829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602116103 |
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