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piggyBac is a flexible and highly active transposon as compared to Sleeping Beauty, Tol2, and Mos1 in mammalian cells

A nonviral vector for highly efficient site-specific integration would be desirable for many applications in transgenesis, including gene therapy. In this study we directly compared the genomic integration efficiencies of piggyBac, hyperactive Sleeping Beauty (SB11), Tol2, and Mos1 in four mammalian...

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Détails bibliographiques
Auteurs principaux: Wu, Sareina Chiung-Yuan, Meir, Yaa-Jyuhn James, Coates, Craig J., Handler, Alfred M., Pelczar, Pawel, Moisyadi, Stefan, Kaminski, Joseph M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2006
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1622771/
https://ncbi.nlm.nih.gov/pubmed/17005721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606979103
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