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piggyBac is a flexible and highly active transposon as compared to Sleeping Beauty, Tol2, and Mos1 in mammalian cells

A nonviral vector for highly efficient site-specific integration would be desirable for many applications in transgenesis, including gene therapy. In this study we directly compared the genomic integration efficiencies of piggyBac, hyperactive Sleeping Beauty (SB11), Tol2, and Mos1 in four mammalian...

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Bibliografiske detaljer
Main Authors: Wu, Sareina Chiung-Yuan, Meir, Yaa-Jyuhn James, Coates, Craig J., Handler, Alfred M., Pelczar, Pawel, Moisyadi, Stefan, Kaminski, Joseph M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1622771/
https://ncbi.nlm.nih.gov/pubmed/17005721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606979103
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