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Mathematical modeling of tumor therapy with oncolytic viruses: effects of parametric heterogeneity on cell dynamics

BACKGROUND: One of the mechanisms that ensure cancer robustness is tumor heterogeneity, and its effects on tumor cells dynamics have to be taken into account when studying cancer progression. There is no unifying theoretical framework in mathematical modeling of carcinogenesis that would account for...

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Bibliographic Details
Main Authors: Karev, Georgy P, Novozhilov, Artem S, Koonin, Eugene V
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1622743/
https://ncbi.nlm.nih.gov/pubmed/17018145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-1-30
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