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Oncolytic potency and reduced virus tumor-specificity in oncolytic virotherapy. A mathematical modelling approach

In the present paper, we address by means of mathematical modeling the following main question: How can oncolytic virus infection of some normal cells in the vicinity of tumor cells enhance oncolytic virotherapy? We formulate a mathematical model describing the interactions between the oncolytic vir...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mahasa, Khaphetsi Joseph, Eladdadi, Amina, de Pillis, Lisette, Ouifki, Rachid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608221/
https://ncbi.nlm.nih.gov/pubmed/28934210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184347
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