Nephrin and CD2AP Associate with Phosphoinositide 3-OH Kinase and Stimulate AKT-Dependent Signaling

Mutations of NPHS1 or NPHS2, the genes encoding nephrin and podocin, as well as the targeted disruption of CD2-associated protein (CD2AP), lead to heavy proteinuria, suggesting that all three proteins are essential for the integrity of glomerular podocytes, the visceral glomerular epithelial cells o...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Huber, Tobias B., Hartleben, Björn, Kim, Jeong, Schmidts, Miriam, Schermer, Bernhard, Keil, Alexander, Egger, Lotti, Lecha, Rachel L., Borner, Christoph, Pavenstädt, Hermann, Shaw, Andrey S., Walz, Gerd, Benzing, Thomas
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2003
Fag:	Cell Growth and Development
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162232/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12832477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.14.4917-4928.2003
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!