Nephrin and CD2AP Associate with Phosphoinositide 3-OH Kinase and Stimulate AKT-Dependent Signaling

Mutations of NPHS1 or NPHS2, the genes encoding nephrin and podocin, as well as the targeted disruption of CD2-associated protein (CD2AP), lead to heavy proteinuria, suggesting that all three proteins are essential for the integrity of glomerular podocytes, the visceral glomerular epithelial cells o...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Huber, Tobias B., Hartleben, Björn, Kim, Jeong, Schmidts, Miriam, Schermer, Bernhard, Keil, Alexander, Egger, Lotti, Lecha, Rachel L., Borner, Christoph, Pavenstädt, Hermann, Shaw, Andrey S., Walz, Gerd, Benzing, Thomas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2003
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162232/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12832477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.14.4917-4928.2003
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