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Combination of Two Activating Mutations in One HOG1 Gene Forms Hyperactive Enzymes That Induce Growth Arrest

Mitogen-activated protein kinases (MAPKs) play key roles in differentiation, growth, proliferation, and apoptosis. Although MAPKs have been extensively studied, the precise function, specific substrates, and target genes of each MAPK are not known. These issues could be addressed by sole activation...

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Detalhes bibliográficos
Main Authors: Yaakov, Gilad, Bell, Michal, Hohmann, Stefan, Engelberg, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162220/
https://ncbi.nlm.nih.gov/pubmed/12832470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.14.4826-4840.2003
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