MAQ1 and 7SK RNA Interact with CDK9/Cyclin T Complexes in a Transcription-Dependent Manner

Positive transcription elongation factor b (P-TEFb) comprises a cyclin (T1 or T2) and a kinase, cyclin-dependent kinase 9 (CDK9), which phosphorylates the carboxyl-terminal domain of RNA polymerase II. P-TEFb is essential for transcriptional elongation in human cells. A highly specific interaction a...

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Hlavní autoři: Michels, Annemieke A., Nguyen, Van Trung, Fraldi, Alessandro, Labas, Valérie, Edwards, Mia, Bonnet, François, Lania, Luigi, Bensaude, Olivier
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Transcriptional Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC162212/
https://ncbi.nlm.nih.gov/pubmed/12832472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.14.4859-4869.2003
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