Signal transduction by a nondissociable heterotrimeric yeast G protein
Many signal transduction pathways involve heterotrimeric G proteins. The accepted model for activation of heterotrimeric G proteins states that the protein dissociates to the free G(α) (GTP)-bound subunit and free G(βγ) dimer. On GTP hydrolysis, G(α) (GDP) then reassociates with G(βγ) [Gilman, A. G....
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2000
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10725354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050015797 |
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