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The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU

Pseudomonas aeruginosa delivers the toxin ExoU to eukaryotic cells via a type III secretion system. Intoxication with ExoU is associated with lung injury, bacterial dissemination and sepsis in animal model and human infections. To search for ExoU targets in a genetically tractable system, we used co...

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Published in:EMBO J
Main Authors: Sato, Hiromi, Frank, Dara W., Hillard, Cecilia J., Feix, Jimmy B., Pankhaniya, Ravi R., Moriyama, Kiyoshi, Finck-Barbançon, Viviane, Buchaklian, Adam, Lei, Ming, Long, Roy M., Wiener-Kronish, Jeanine, Sawa, Teiji
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2003
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162142/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12805211/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg290
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