The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU

Pseudomonas aeruginosa delivers the toxin ExoU to eukaryotic cells via a type III secretion system. Intoxication with ExoU is associated with lung injury, bacterial dissemination and sepsis in animal model and human infections. To search for ExoU targets in a genetically tractable system, we used co...

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Main Authors: Sato, Hiromi, Frank, Dara W., Hillard, Cecilia J., Feix, Jimmy B., Pankhaniya, Ravi R., Moriyama, Kiyoshi, Finck-Barbançon, Viviane, Buchaklian, Adam, Lei, Ming, Long, Roy M., Wiener-Kronish, Jeanine, Sawa, Teiji
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC162142/
https://ncbi.nlm.nih.gov/pubmed/12805211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg290
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