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Effects of the novel selective endothelin ET(A) receptor antagonist, SB 234551, on the cardiovascular responses to endotoxaemia in conscious rats

1. In conscious, freely moving, male, Long Evans rats, regional haemodynamic responses to exogenous endothelin-1 (ET-1; 25, 50 and 250 pmol kg(−1) i.v.) were assessed in the presence of vehicle, or the selective ET(A)-receptor antagonist, SB 234551. On the following day, the effects of SB 234551 on...

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Detalhes bibliográficos
Main Authors: Gardiner, S M, March, J E, Kemp, P A, Bennett, T
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1621154/
https://ncbi.nlm.nih.gov/pubmed/11498524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704202
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