Effects of the novel selective endothelin ET(A) receptor antagonist, SB 234551, on the cardiovascular responses to endotoxaemia in conscious rats

1. In conscious, freely moving, male, Long Evans rats, regional haemodynamic responses to exogenous endothelin-1 (ET-1; 25, 50 and 250 pmol kg(−1) i.v.) were assessed in the presence of vehicle, or the selective ET(A)-receptor antagonist, SB 234551. On the following day, the effects of SB 234551 on...

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Bibliografiske detaljer
Main Authors: Gardiner, S M, March, J E, Kemp, P A, Bennett, T
Format: Artigo
Sprog:Inglês
Udgivet: 2001
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Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1621154/
https://ncbi.nlm.nih.gov/pubmed/11498524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704202
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