Cardiovascular effects of endothelin-1 and endothelin antagonists in conscious, hypertensive ((mRen-2)27) rats

1. SB 209670 is a potent antagonist of the vasoconstrictor (ET(A)- and ET(B)-receptor-mediated) and vasodilator (ET(B)-receptor-mediated) effects of endothelin, whereas SB 234551 is relatively selective for the constrictor (ET(A)-receptor-mediated) effects. Since we had previously found SB 209670 ex...

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Hlavní autoři: Gardiner, S M, March, J E, Kemp, P A, Bennett, T
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572520/
https://ncbi.nlm.nih.gov/pubmed/11139453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703767
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