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Impaired nucleotide excision repair upon macrophage differentiation is corrected by E1 ubiquitin-activating enzyme

Global nucleotide excision repair is greatly attenuated in terminally differentiated mammalian cells. We observed this phenomenon in human neurons and in macrophages, noting that the transcription-coupled repair pathway remains functional and that there is no significant reduction in levels of excis...

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Autors principals: Nouspikel, Thierry, Hanawalt, Philip C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1621053/
https://ncbi.nlm.nih.gov/pubmed/17060614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607769103
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