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Distinct functions of the ubiquitin–proteasome pathway influence nucleotide excision repair

The Rad23/Rad4 nucleotide excision repair (NER) protein complex functions at an early stage of the NER reaction, possibly promoting the recognition of damaged DNA. Here we show that Rad4 protein is ubiquitinated and degraded in response to ultraviolet (UV) radiation, and identify a novel cullin-base...

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Detalles Bibliográficos
Main Authors: Gillette, Thomas G, Yu, Shirong, Zhou, Zheng, Waters, Raymond, Johnston, Stephen Albert, Reed, Simon H
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1478203/
https://ncbi.nlm.nih.gov/pubmed/16675952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601120
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