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Distinct functions of the ubiquitin–proteasome pathway influence nucleotide excision repair

The Rad23/Rad4 nucleotide excision repair (NER) protein complex functions at an early stage of the NER reaction, possibly promoting the recognition of damaged DNA. Here we show that Rad4 protein is ubiquitinated and degraded in response to ultraviolet (UV) radiation, and identify a novel cullin-base...

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Main Authors: Gillette, Thomas G, Yu, Shirong, Zhou, Zheng, Waters, Raymond, Johnston, Stephen Albert, Reed, Simon H
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1478203/
https://ncbi.nlm.nih.gov/pubmed/16675952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601120
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