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The insertion of two amino acids into a transcriptional inducer converts it into a galactokinase

The transcriptional induction of the GAL genes of Saccharomyces cerevisiae occurs when galactose and ATP interact with Gal3p. This protein-small molecule complex associates with Gal80p to relieve its inhibitory effect on the transcriptional activator Gal4p. Gal3p shares a high degree of sequence hom...

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Autors principals: Platt, Adam, Ross, Helen C., Hankin, Steven, Reece, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC16208/
https://ncbi.nlm.nih.gov/pubmed/10737789
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