BRCA1 interaction with RNA polymerase II reveals a role for hRPB2 and hRPB10α in activated transcription

The functions of most of the 12 subunits of the RNA polymerase II (Pol II) enzyme are unknown. In this study, we demonstrate that two of the subunits, hRPB2 and hRPB10α, mediate the regulated stimulation of transcription. We find that the transcriptional coactivator BRCA1 interacts directly with the...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Schlegel, Brian P., Green, Victoria J., Ladias, John A. A., Parvin, Jeffrey D.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 2000
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16207/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10725406/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.070452397
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