Combined Contributions of Streptolysin O and Streptolysin S to Virulence of Serotype M5 Streptococcus pyogenes Strain Manfredo

Streptolysin O (SLO) and streptolysin S (SLS) are potent cytolytic toxins produced by almost all clinical isolates of group A streptococci (GAS). Allele-replacement mutagenesis was used to construct nonpolar (in-frame) deletion mutations in the slo and sagB genes of the serotype M5 GAS strain Manfre...

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Publié dans:	Infect Immun
Auteurs principaux:	Fontaine, Michael C., Lee, Jeong Jin, Kehoe, Michael A.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2003
Sujets:	Molecular Pathogenesis
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162000/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12819070/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.7.3857-3865.2003
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