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BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

A change of mitochondrial membrane permeability is essential for apoptosis, leading to translocation of apoptogenic cytochrome c and apoptosis-inducing factor into the cytoplasm. We recently showed that the Bcl-2 family of proteins regulate cytochrome c release and the mitochondrial membrane potenti...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Shimizu, Shigeomi, Konishi, Akimitsu, Kodama, Takashi, Tsujimoto, Yoshihide
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16199/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10737788/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.7.3100
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