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Isoleucine-15 of rainbow trout carbonyl reductase-like 20β-hydroxysteroid dehydrogenase is critical for coenzyme (NADPH) binding

Carbonyl reductase-like 20β-hydroxysteroid dehydrogenase (CR/20β-HSD) is an enzyme that converts 17α-hydroxyprogesterone to 17α,20β-dihydroxy-4-pregnen-3-one (the maturation-inducing hormone of salmonid fish). We have previously isolated two types of CR/20β-HSD cDNAs from ovarian follicle of rainbow...

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Detalhes bibliográficos
Main Authors: Guan, Guijun, Todo, Takashi, Tanaka, Minoru, Young, Graham, Nagahama, Yoshitaka
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16195/
https://ncbi.nlm.nih.gov/pubmed/10725344
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