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Activation and Inhibition of Cellular Calcium and Tyrosine Kinase Signaling Pathways Identify Targets of the HBx Protein Involved in Hepatitis B Virus Replication

Human hepatitis B virus (HBV) HBx protein is a multifunctional protein that activates cellular signaling pathways and is thought to be essential for viral infection. Woodchuck HBV mutants that lack HBx are unable to replicate in vivo or are severely impaired. HBV replication in HepG2 cells, a human...

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Bibliografiske detaljer
Main Authors: Bouchard, Michael J., Puro, Robyn J., Wang, Lihua, Schneider, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC161925/
https://ncbi.nlm.nih.gov/pubmed/12829810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.14.7713-7719.2003
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