Activation and Inhibition of Cellular Calcium and Tyrosine Kinase Signaling Pathways Identify Targets of the HBx Protein Involved in Hepatitis B Virus Replication

Human hepatitis B virus (HBV) HBx protein is a multifunctional protein that activates cellular signaling pathways and is thought to be essential for viral infection. Woodchuck HBV mutants that lack HBx are unable to replicate in vivo or are severely impaired. HBV replication in HepG2 cells, a human...

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Autores principales: Bouchard, Michael J., Puro, Robyn J., Wang, Lihua, Schneider, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC161925/
https://ncbi.nlm.nih.gov/pubmed/12829810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.14.7713-7719.2003
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