Delivery of Adeno-Associated Virus Vectors to the Fetal Retina: Impact of Viral Capsid Proteins on Retinal Neuronal Progenitor Transduction

The development of fetal ocular gene transfer may be useful as a therapeutic tool for the prevention of retinal genetic disorders with congenital or early clinical manifestations. In this study we explored the neural progenitor transduction patterns of adeno-associated virus (AAV) vectors following...

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Detalhes bibliográficos
Main Authors: Surace, Enrico M., Auricchio, Alberto, Reich, Samuel J., Rex, Tonia, Glover, Ernest, Pineles, Stacey, Tang, Waixing, O'Connor, Erin, Lyubarsky, Arkady, Savchenko, Andrey, Pugh, Edward N., Maguire, Albert M., Wilson, James M., Bennett, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC161923/
https://ncbi.nlm.nih.gov/pubmed/12829835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.14.7957-7963.2003
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