Delivery of Adeno-Associated Virus Vectors to the Fetal Retina: Impact of Viral Capsid Proteins on Retinal Neuronal Progenitor Transduction

The development of fetal ocular gene transfer may be useful as a therapeutic tool for the prevention of retinal genetic disorders with congenital or early clinical manifestations. In this study we explored the neural progenitor transduction patterns of adeno-associated virus (AAV) vectors following...

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Détails bibliographiques
Auteurs principaux: Surace, Enrico M., Auricchio, Alberto, Reich, Samuel J., Rex, Tonia, Glover, Ernest, Pineles, Stacey, Tang, Waixing, O'Connor, Erin, Lyubarsky, Arkady, Savchenko, Andrey, Pugh, Edward N., Maguire, Albert M., Wilson, James M., Bennett, Jean
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
Sujets:
Gene Therapy
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC161923/
https://ncbi.nlm.nih.gov/pubmed/12829835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.14.7957-7963.2003
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