Delivery of Adeno-Associated Virus Vectors to the Fetal Retina: Impact of Viral Capsid Proteins on Retinal Neuronal Progenitor Transduction

The development of fetal ocular gene transfer may be useful as a therapeutic tool for the prevention of retinal genetic disorders with congenital or early clinical manifestations. In this study we explored the neural progenitor transduction patterns of adeno-associated virus (AAV) vectors following...

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Bibliographic Details
Main Authors: Surace, Enrico M., Auricchio, Alberto, Reich, Samuel J., Rex, Tonia, Glover, Ernest, Pineles, Stacey, Tang, Waixing, O'Connor, Erin, Lyubarsky, Arkady, Savchenko, Andrey, Pugh, Edward N., Maguire, Albert M., Wilson, James M., Bennett, Jean
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Gene Therapy
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC161923/
https://ncbi.nlm.nih.gov/pubmed/12829835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.14.7957-7963.2003
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