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Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity

Several mammalian cytochrome P450 (P450) isoforms demonstrate homotropic cooperativity with a number of substrates, including steroids and polycyclic aromatic hydrocarbons. To identify structural factors contributing to steroid and polycyclic aromatic hydrocarbon binding to P450 enzymes and to deter...

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Detalhes bibliográficos
Main Authors: Cupp-Vickery, Jill, Anderson, Robert, Hatziris, Zena
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16190/
https://ncbi.nlm.nih.gov/pubmed/10716705
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