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Synthetic promoter elements obtained by nucleotide sequence variation and selection for activity

Eukaryotic transcriptional regulation in different cells involves large numbers and arrangements of cis and trans elements. To survey the number of cis regulatory elements that are active in different contexts, we have devised a high-throughput selection procedure permitting synthesis of active cis...

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Detalhes bibliográficos
Main Authors: Edelman, Gerald M., Meech, Robyn, Owens, Geoffrey C., Jones, Frederick S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16188/
https://ncbi.nlm.nih.gov/pubmed/10725347
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