Synthetic promoter elements obtained by nucleotide sequence variation and selection for activity

Eukaryotic transcriptional regulation in different cells involves large numbers and arrangements of cis and trans elements. To survey the number of cis regulatory elements that are active in different contexts, we have devised a high-throughput selection procedure permitting synthesis of active cis...

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Bibliographic Details
Main Authors: Edelman, Gerald M., Meech, Robyn, Owens, Geoffrey C., Jones, Frederick S.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC16188/
https://ncbi.nlm.nih.gov/pubmed/10725347
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