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Minodronate, a Newly Developed Nitrogen-Containing Bisphosphonate, Suppresses Melanoma Growth and Improves Survival in Nude Mice by Blocking Vascular Endothelial Growth Factor Signaling
Angiogenesis, a process by which new vascular networks are formed from pre-existing capillaries, is required for tumors to grow, invade, and metastasize. Vascular endothelial growth factor (VEGF), a specific mitogen to endothelial cells, is a crucial factor for tumor angiogenesis. In this study, we...
Kaydedildi:
Asıl Yazarlar: | , , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
American Society for Investigative Pathology
2004
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1618714/ https://ncbi.nlm.nih.gov/pubmed/15579431 |
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