Thrombospondin 2 Functions as an Endogenous Regulator of Angiogenesis and Inflammation in Rheumatoid Arthritis

Thrombospondin 2 (TSP2), a matricellular protein with a primary role in modulating cell-matrix interactions, has been implicated in tissue repair and foreign body responses. Here we show that TSP2 has regulatory function in the chronic inflammatory lesions of rheumatoid arthritis. Tissue TSP2, produ...

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Bibliographic Details
Main Authors: Park, Yong Wook, Kang, Young Mo, Butterfield, Joe, Detmar, Michael, Goronzy, Jörg J., Weyand, Cornelia M.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2004
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Original Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618704/
https://ncbi.nlm.nih.gov/pubmed/15579451
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