Cell Tropism of Simian Immunodeficiency Virus in Culture Is Not Predictive of in Vivo Tropism or Pathogenesis

SIVmac239/316 is a molecular clone derived from SIVmac239 that differs from the parental virus by nine amino acids in env. This virus, unlike the parental SIVmac239, is able to replicate well in alveolar macrophages in culture. We have not however, observed macrophage-associated inflammatory disease...

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Main Authors: Borda, Juan T., Alvarez, Xavier, Kondova, Ivanela, Aye, Pyone, Simon, Meredith A., Desrosiers, Ronald C., Lackner, Andrew A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
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Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618703/
https://ncbi.nlm.nih.gov/pubmed/15579453
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