Gastrointestinal Disease in Simian Immunodeficiency Virus-Infected Rhesus Macaques Is Characterized by Proinflammatory Dysregulation of the Interleukin-6-Janus Kinase/Signal Transducer and Activator of Transcription3 Pathway

Gastrointestinal disease and inflammation are common sequelae of human and simian immunodeficiency virus (SIV) infection. Nevertheless, the molecular mechanisms that lead to gastrointestinal dysfunction remain unclear. We investigated regulation of the interleukin (IL)-6-JAK-STAT3 pathway in jejunum...

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Detalhes bibliográficos
Main Authors: Mohan, Mahesh, Aye, Pyone P., Borda, Juan T., Alvarez, Xavier, Lackner, Andrew A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111118/
https://ncbi.nlm.nih.gov/pubmed/18055558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070017
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