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Synaptic Changes in Alzheimer’s Disease : Increased Amyloid-β and Gliosis in Surviving Terminals Is Accompanied by Decreased PSD-95 Fluorescence
In an effort to examine changes that precede synapse loss, we have measured amyloid-β and a series of damage markers in the synaptic compartment of Alzheimer’s disease (AD) cases. Because localization of events to the terminal region in neurons is problematic with conventional methods, we prepared s...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Investigative Pathology
2004
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1618663/ https://ncbi.nlm.nih.gov/pubmed/15509549 |
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