Intra- and Interindividual Variabilities of Valacyclovir Oral Bioavailability and Effect of Coadministration of an hPEPT1 Inhibitor

Variability in valacyclovir bioavailability and the potential for cephalexin-valacyclovir interaction were evaluated. The intraindividual acyclovir area under the concentration-time curve (AUC) varied minimally, whereas interindividual differences were substantial. Coadministration of the human pept...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Phan, Dana D., Chin-Hong, Peter, Lin, Emil T., Anderle, Pascale, Sadee, Wolfgang, Guglielmo, B. Joseph
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12821497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.7.2351-2353.2003
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