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Intra- and Interindividual Variabilities of Valacyclovir Oral Bioavailability and Effect of Coadministration of an hPEPT1 Inhibitor

Variability in valacyclovir bioavailability and the potential for cephalexin-valacyclovir interaction were evaluated. The intraindividual acyclovir area under the concentration-time curve (AUC) varied minimally, whereas interindividual differences were substantial. Coadministration of the human pept...

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Phan, Dana D., Chin-Hong, Peter, Lin, Emil T., Anderle, Pascale, Sadee, Wolfgang, Guglielmo, B. Joseph
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161865/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12821497/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.7.2351-2353.2003
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