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Severe Pancreatitis with Exocrine Destruction and Increased Islet Neogenesis in Mice with Suppressor of Cytokine Signaling-1 Deficiency

Mice with suppressor of cytokine signaling-1 (SOCS-1) deficiency die within 3 weeks of birth from a multiorgan inflammatory disease. Increased systemic levels and sensitivity of cells to the inflammatory cytokines interferon-γ and tumor necrosis factor may contribute to the disease. Hepatitis and li...

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Detalhes bibliográficos
Main Authors: Chen, Ye, Chong, Mark M.W., Darwiche, Rima, Thomas, Helen E., Kay, Thomas W.H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618606/
https://ncbi.nlm.nih.gov/pubmed/15331415
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