Near Completely Humanized Liver in Mice Shows Human-Type Metabolic Responses to Drugs

Human hepatocytes were transplanted into urokinase-type plasminogen activator-transgenic SCID mice (uPA/SCID mice), which are immunodeficient and undergo liver failure. The transplanted cells were characterized in terms of their in vivo growth potential and functions. The human hepatocytes progressi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Tateno, Chise, Yoshizane, Yasumi, Saito, Naomi, Kataoka, Miho, Utoh, Rie, Yamasaki, Chihiro, Tachibana, Asato, Soeno, Yoshinori, Asahina, Kinji, Hino, Hiroshi, Asahara, Toshimasa, Yokoi, Tsuyoshi, Furukawa, Toshinori, Yoshizato, Katsutoshi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2004
Aiheet:
Regular Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618591/
https://ncbi.nlm.nih.gov/pubmed/15331414
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