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Pleiotrophin/Heparin-Binding Growth-Associated Molecule as a Mitogen of Rat Hepatocytes and Its Role in Regeneration and Development of Liver

Previously pleiotrophin (PTN) was identified among proteins secreted by Swiss 3T3 cells as a mitogen for cultured adult rat hepatocytes. The present study showed that the growth of rat hepatocytes was enhanced when cultured with rat hepatic stellate cells (HSCs). HSCs expressed PTN mRNA and secreted...

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Autori principali: Asahina, Kinji, Sato, Hajime, Yamasaki, Chihiro, Kataoka, Miho, Shiokawa, Miho, Katayama, Shigeru, Tateno, Chise, Yoshizato, Katsutoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850835/
https://ncbi.nlm.nih.gov/pubmed/12057922
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