Lack of Integrin α1β1 Leads to Severe Glomerulosclerosis after Glomerular Injury

Severity of fibrosis after injury is determined by the nature of the injury and host genetic susceptibility. Metabolism of collagen, the major component of fibrotic lesions, is, in part, regulated by integrins. Using a model of glomerular injury by adriamycin, which induces reactive oxygen species (...

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Autores principales: Chen, Xiwu, Moeckel, Gilbert, Morrow, Jason D., Cosgrove, Dominic, Harris, Raymond C., Fogo, Agnes B., Zent, Roy, Pozzi, Ambra
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2004
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Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618576/
https://ncbi.nlm.nih.gov/pubmed/15277235
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