Cathepsin K Is the Principal Protease in Giant Cell Tumor of Bone

Giant cell tumor (GCT) of bone is a neoplasm of bone characterized by a localized osteolytic lesion. The nature of GCT is an enigma and the cell type(s) and protease(s) responsible for the extensive localized clinicoradiological osteolysis remain unresolved. We evaluated protease expression and cell...

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Autori principali: Lindeman, Jan H.N., Hanemaaijer, Roeland, Mulder, Adri, Dijkstra, P.D. Sander, Szuhai, Károly, Bromme, Dieter, Verheijen, Jan H., Hogendoorn, Pancras C.W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618565/
https://ncbi.nlm.nih.gov/pubmed/15277232
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