Overexpression of PDZK1 within the 1q12-q22 Amplicon Is Likely To Be Associated with Drug-Resistance Phenotype in Multiple Myeloma

We investigated DNA copy number aberrations in 37 cell lines derived from multiple myelomas (MMs) using comparative genomic hybridization, and 11 (29.7%) showed high-level gain indicative of gene amplification at 1q12-q22. A corresponding transcriptional mapping using oligonucleotide arrays extracte...

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Main Authors: Inoue, Jun, Otsuki, Takemi, Hirasawa, Akira, Imoto, Issei, Matsuo, Yoshinobu, Shimizu, Shiroh, Taniwaki, Masafumi, Inazawa, Johji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618545/
https://ncbi.nlm.nih.gov/pubmed/15215163
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