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HECT-type Ubiquitin Ligase ITCH Targets Lysosomal-associated Protein Multispanning Transmembrane 5 (LAPTM5) and Prevents LAPTM5-mediated Cell Death

LAPTM5 (lysosomal-associated protein multispanning transmembrane 5) is a membrane protein on the intracellular vesicles. We have previously demonstrated that the accumulation of LAPTM5-positive vesicles was closely associated with the programmed cell death occurring during the spontaneous regression...

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Detalhes bibliográficos
Main Authors: Ishihara, Takaya, Inoue, Jun, Kozaki, Ken-ichi, Imoto, Issei, Inazawa, Johji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243552/
https://ncbi.nlm.nih.gov/pubmed/22009753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.251694
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