The Cytoplasmic Domain of Tissue Factor Contributes to Leukocyte Recruitment and Death in Endotoxemia

Tissue factor (TF) is an integral membrane protein that binds factor VIIa and initiates coagulation. The extracellular domain of TF is responsible for its hemostatic function and by implication in the dysregulation of coagulation, which contributes to death in endotoxemia. The role of the cytoplasmi...

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Main Authors: Sharma, Laveena, Melis, Els, Hickey, Michael J., Clyne, Colin D., Erlich, Jonathan, Khachigian, Levon M., Davenport, Piers, Morand, Eric, Carmeliet, Peter, Tipping, Peter G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2004
Ábhair:
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618541/
https://ncbi.nlm.nih.gov/pubmed/15215187
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