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Reduction in Arthritis Severity and Modulation of Immune Function in Tissue Factor Cytoplasmic Domain Mutant Mice

Tissue factor (TF), a transmembrane receptor for plasma factor VII(a), is the main initiator of the coagulation cascade. It has also been implicated in noncoagulant processes, including inflammation. The function of the TF cytoplasmic domain was studied in mice in which 18 of the 20 cytoplasmic amin...

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Detalhes bibliográficos
Main Authors: Yang, Yuan H., Hall, Pam, Milenkovski, Georgia, Sharma, Laveena, Hutchinson, Paul, Melis, Els, Carmeliet, Peter, Tipping, Peter, Morand, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602216/
https://ncbi.nlm.nih.gov/pubmed/14695325
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