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Modelling cell lifespan and proliferation: is likelihood to die or to divide independent of age?

In cell lifespan studies the exponential nature of cell survival curves is often interpreted as showing the rate of death is independent of the age of the cells within the population. Here we present an alternative model where cells that die are replaced and the age and lifespan of the population po...

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Detalhes bibliográficos
Main Authors: Dowling, Mark R, Milutinović, Dejan, Hodgkin, Philip D
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618504/
https://ncbi.nlm.nih.gov/pubmed/16849210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2005.0069
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